The article is devoted to the analysis of European written sources that prove the political and cultural aspects of the Hephthalite state - a state that existed in the early Middle Ages in modern Kazakhstan and Central Asia. Hephthalite or «White Huns» - a nomadic, military state that reached the imperial level. Currently, there is a need to study the issues of the go-political situation in Central Asia in the period before Islam, cultural exchange, political-economic relations, problems of ethnolinguistics based on sources and research, and as a result of this, it is necessary to form an objective approach. In Kazakhstani science there are virtually no research works devoted to studying the issue of the place and role of the Hephthalites in the Turkic world. Therefore, in the work the authors draw conclusions based on medieval European written sources, including sources in the Vatican funds. In the Middle Ages, the Hephthalites, as a military-politically developing state in Central Asia, were able to culturally develop their economy and diplomatic relations. Participating in the ethno-confessional life of the living peoples, they were guided by the preservation of peace and harmony. The article focuses on the issue of tolerance; religious views already in that period became one of the main tools for the comprehensive development of the state. The development of cultural and spiritual ties, issues of ethnocultural exchange between the Ephthalite state and the peoples of Central Asia are considered from the point of view of a historical approach. The topic of the scientific article determines a specific aspect of the issue - the political role of cultural and spiritual ties between the Hephthalites and Turkic tribes. Issues of integration, historical significance, and influence on the acceptance of new states and political associations into the political arena are considered. For example, the influence of the Hephthalites, who played an important role in the formation of the Avar tribal association, has been proven on the basis of written sources. The scientific research used systematic historical-comparative and comparative-typological methods, the use of which made it possible to obtain the most complete picture of the history of the Hephthalite state. The methodological basis of the study is the principles of historicism, the unity of national and universal values ​​and the dialectical approach to the study of historical processes. In accordance with this point of view, in this study the history of the Hephthalite state is considered as a significant era in the history of the peoples of Central Asia. In addition, significant conclusions have been formulated on issues of Hephthalite culture and general problems for the Turkic peoples.